Resurgence of dengue serotype DENV-03 in Puerto Rico

July 5, 2026

In the last year, a change in the predominant dengue serotype has been observed in Puerto Rico.

Following the 2024-2025 epidemic, the DENV-03 serotype, absent for more than 20 years, now accounts for 100% of registered cases. This resurgence raises questions about public health on the island.

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